Too short and too poor: A tale of two siblings

Reducing Cardiovascular Risk: Too Little, Too Late, Too Short-Term

Vascular diseases in general, and cardiovascular disease in particular, are diseases of mass destruction, killing more people in the Western world (and increasingly in the developing world) than world wars. Each year, coronary heart disease kills over half a million Americans and over 100 000 British citizens each year, often prematurely (WHO online). A combination of migration, epidemiological...

A Tale of Too Many Centrosomes

Having the correct number of centrosomes is crucial for proper chromosome segregation during cell division and for the prevention of aneuploidy, a hallmark of many cancer cells. Several recent studies (Basto et al., 2008; Kwon et al., 2008; Yang et al., 2008) reveal the importance of mechanisms that protect against the consequences of harboring too many centrosomes.

XML Publishing: Look at Siblings too!

In order to publish a nested XML document from flat relational data, multiple SQL queries are often needed. The efficiency of publishing relies on how fast these queries can be evaluated and their results shipped to the client. We illustrate novel optimization techniques that enable computation sharing between queries that construct sibling elements in the XML tree. Such queries typically share...

The QT interval: too long, too short or just right.

Two hats too many

We view ourselves as scientists as very intelligent, extremely hard-working, and highly creative, though perhaps more competitive than we care to admit. But no one seems to recognize the high incidence of a serious medical problem among investigators — 'multiple personality disorder'. Of course I say this with tongue planted firmly in cheek, but it's not too far off the mark when we consider ou...